In my experience it seems that most people will tell you that it is unwise to force a garbage collection but in some cases where you are working with large objects that don't always get collected in the 0 generation but where memory is an issue, is it ok to force the collect? Is there a best practice out there for doing so?
The best practise is to not force a garbage collection.
According to MSDN:
"It is possible to force garbage collection by calling Collect, but most of the time, this should be avoided because it may create performance issues. "
However, if you can reliably test your code to confirm that calling Collect() won't have a negative impact then go ahead...
Just try to make sure objects are cleaned up when you no longer need them. If you have custom objects, look at using the "using statement" and the IDisposable interface.
This link has some good practical advice with regards to freeing up memory / garbage collection etc:
The best practise is to not force a garbage collection in most cases. (Every system I have worked on that had forced garbage collections, had underlining problems that if solved would have removed the need to forced the garbage collection, and sped the system up greatly.)
There are a few cases when you know more about memory usage then the garbage collector does. This is unlikely to be true in a multi user application, or a service that is responding to more then one request at a time.
However in some batch type processing you do know more then the GC. E.g. consider an application that.
You may be able to make a case (after careful) testing that you should force a full garbage collection after you have process each file.
Another cases is a service that wakes up every few minutes to process some items, and does not keep any state while it’s asleep. Then forcing a full collection just before going to sleep may be worthwhile.
The only time I would consider forcing a collection is when I know that a lot of object had been created recently and very few objects are currently referenced.
I would rather have a garbage collection API when I could give it hints about this type of thing without having to force a GC my self.
See also "Rico Mariani's Performance Tidbits"